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Hospital Harm - Opioid-Related Adverse Events

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Table Options
Measure Information 2024 Reporting Period
Title Hospital Harm - Opioid-Related Adverse Events
CMS eCQM ID CMS819v2
Short Name

HH-ORAE

CBE ID* 3501e
Measure Steward Centers for Medicare & Medicaid Services (CMS)
Description

This measure assesses the number of inpatient hospitalizations for patients age 18 and older who have been administered an opioid medication and are subsequently administered an opioid antagonist within 12 hours, an indication of an opioid-related adverse event

Measure Scoring Proportion
Measure Type Outcome
Stratification

None

Risk Adjustment

None

Rationale

Opioids are often the foundation for sedation and pain relief. Opioid-based analgesia continues to be the most commonly used treatment in postoperative pain management, with more than 95% of surgical patients receiving opioids during their hospitalization (Baker et al., 2020). However,...

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Clinical Recommendation Statement

Naloxone is an opioid reversal agent typically used for severe opioid-related adverse events. Naloxone administration has been used in a number of studies as an indicator of opioid-related adverse events (Lynn et al., 2017, Nwulu et al., 2013).

From Section 10 of the 2015 American Heart...

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Improvement Notation

A lower proportion indicates higher quality

Definition

This measure defines the indication of a harm for an opioid-related adverse event by assessing administration of an opioid antagonist.

Inpatient hospitalizations: Includes time in the emergency department and observation when the transition between these encounters (if they exist) and the...

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Guidance

To calculate the hospital-level measure result, divide the total numerator events by the total number of qualifying encounters (denominator).

Qualifying encounters (denominator) include all patients 18 years of age or older with at least one opioid medication administered outside of the...

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Initial Population

Inpatient hospitalizations for patients age 18 and older during which at least one opioid medication was administered outside of the operating room

Denominator

Equals Initial Population

Denominator Exclusions

None

Numerator

Inpatient hospitalizations where an opioid antagonist was administered outside of the operating room and within 12 hours following administration of an opioid medication. The route of administration of the opioid antagonist must be by intranasal spray, inhalation, intramuscular,...

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Numerator Exclusions

Not applicable

Denominator Exceptions

None

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Last Updated: May 01, 2025