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Safe Use of Opioids - Concurrent Prescribing

Compare Versions of: "Safe Use of Opioids - Concurrent Prescribing"

The Compare function compares two years of the measure specifications found in the header of the measure's HTML. It does not include a comparison of any information in the body of the HTML, e.g., population criteria, Clinical Quality Language, or value sets.

Strikethrough text highlighted in red indicates information changed from the previous version. Text highlighted in green indicates information updated in the new eCQM version.

Compare 2026 version to

Table Options
Measure Information 2026 Reporting Period
Title Safe Use of Opioids - Concurrent Prescribing
CMS eCQM ID CMS506v8
CBE ID* 3316e
Measure Steward Centers for Medicare & Medicaid Services (CMS)
Description

Proportion of inpatient hospitalizations for patients 18 years of age and older prescribed, or continued on, two or more opioids or an opioid and benzodiazepine concurrently at discharge

Measure Scoring Proportion measure
Measure Type Process
Stratification

None

Risk Adjustment

None

Rationale

Unintentional opioid overdose fatalities have become a major public health concern in the United States (Rudd, Aleshire, Zibbel, & Gladden, 2016). Reducing the number of unintentional overdoses has become a priority for numerous federal organizations including, but not limited to, the...

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Clinical Recommendation Statement

The CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 recommends that clinicians should:

- “[Use strategies minimizing] opioid use…for both opioid-naïve and opioid-tolerant patients with acute pain when possible. If patients receiving long-term opioid...

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Improvement Notation

Decreased score indicates improvement

Definition

For the purpose of this measure, the following are defined as:

- Opioid: Schedule II, III and IV Opioid Medications that do not include naloxone.

- Benzodiazepine: Schedule IV benzodiazepine medications.

- Medications for Opioid Use Disorder: Methadone, buprenorphine and buprenorphine in...

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Guidance

Clinician judgement, clinical appropriateness, or both may indicate concurrent prescribing of two unique opioids or an opioid and benzodiazepine is medically necessary, thus the measure is not expected to have a zero rate.

New or continuing opioid and benzodiazepine medications are...

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Initial Population

Inpatient hospitalizations that end during the measurement period, where the patient is 18 years of age and older at the start of the encounter and prescribed one opioid and/or benzodiazepine at discharge

Denominator

Equals Initial Population

Denominator Exclusions

Inpatient hospitalizations where patients have cancer pain that begins prior to or during the encounter or are ordered or are receiving palliative or hospice care (including comfort measures, terminal care, and dying care) during the hospitalization or in an emergency department...

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Numerator

Inpatient hospitalizations where the patient is prescribed two or more opioids or an opioid and benzodiazepine at discharge

Numerator Exclusions

None

Denominator Exceptions

None

Next Version No Version Available
Previous Version

Header

TRN

Measure Section

Source of Change

Updated 'eCQM Identifier (Measure Authoring Tool)' field to 'CMS ID' based on tooling update.

CMS ID

Standards/Technical Update

Updated the eCQM version number.

eCQM Version Number

Annual Update

Updated measurement period to reflect exact dates of reporting.

Measurement Period

Standards/Technical Update

Updated copyright.

Copyright

Annual Update

Updated Improvement Notation field to read 'Decreased score indicates improvement' based on tooling update to promote alignment across measures.

Improvement Notation

Standards/Technical Update

Removed narrative references to 'new or continuing opioids' when discussing discharge medications and added language to define the Quality Data Model 'Medication, Discharge' datatype to align with the measure intent and improve clarity.

Multiple Sections

Measure Lead

Removed 'or more' and changed 'or' to 'and/or' in Initial Population narrative description to align with measure intent.

Initial Population

Measure Lead

Updated Denominator Exclusions to specify that patients who are receiving medication for opioid use disorder (OUD) must also have an active OUD diagnosis or be receiving an intervention of opioid medication assisted treatment (MAT) to meet the exclusion criteria, resolving a known issue with the measure.

Denominator Exclusions

ONC Project Tracking System (JIRA): CQM-7018

Updated Numerator Exclusions field to read 'None' instead of 'Not Applicable' when no exclusions present to promote alignment across header fields.

Numerator Exclusions

Standards/Technical Update

Updated references and measure header to reflect current evidence and new or updated literature.

Multiple Sections

Measure Lead

Updated grammar, wording, and/or formatting to improve readability and consistency.

Multiple Sections

Annual Update

Logic

TRN

Measure Section

Source of Change

Re-ordered cancer-related pain Denominator Exclusion logic for improved readability.

Denominator Exclusions

Measure Lead

Updated sickle cell disease exclusion logic to use 'overlaps day of' instead of 'overlaps' to promote alignment of logic patterns used in Denominator Exclusions.

Denominator Exclusions

ONC Project Tracking System (JIRA): CQM-7281

Added logic to identify an active opioid use disorder diagnosis to the 'Treatment for Opioid Use Disorder' definition used for the measure's Denominator Exclusions to align with measure intent.

Definitions

ONC Project Tracking System (JIRA): CQM-7018

Updated the CQL library name from 'CMS506-v7-0-000-QDM-5-6.cql' to 'CMS506SafeUseofOpioids-8.2.000.cql' based on recommendation by technical experts.

Definitions

Standards/Technical Update

Updated comment in 'Inpatient Encounters With An Opioid Or Benzodiazepine At Discharge' logic definition to remove 'or a combination of these medications' to align with measure intent.

Definitions

Measure Lead

Updated sickle cell disease exclusion logic to use 'overlaps day of' instead of 'overlaps' to promote alignment of logic patterns used in Denominator Exclusions.

Definitions

ONC Project Tracking System (JIRA): CQM-7281

Updated the names of CQL definitions, functions, and/or aliases for clarification and to align with the CQL Style Guide.

Definitions

Standards/Technical Update

Updated the version number of the Global Shared Library to v9.0.000 and the library name from 'MATGlobalCommonFunctionsQDM' to 'CQMCommonQDM'.

Definitions

Annual Update

Updated the version number of the Global Shared Library to v9.0.000 and the library name from 'MATGlobalCommonFunctionsQDM' to 'CQMCommonQDM'.

Functions

Annual Update

Value Set

The VSAC is the source of truth for the value set content, please visit the VSAC for downloads of current value sets.

TRN

Measure Section

Source of Change

Replaced value set used for Sex Supplemental Data Element (SDE) ONC Administrative Sex (2.16.840.1.113762.1.4.1) with value set Federal Administrative Sex (2.16.840.1.113762.1.4.1021.121) based on updated standards.

Terminology

Standards/Technical Update

Value set Opioid Medication Assisted Treatment (MAT) (2.16.840.1.113762.1.4.1111.177): Deleted 1 CPT code (HG) based on applicability of value set and/or OID.

Terminology

Annual Update

Value set Schedule II, III and IV Opioid Medications (2.16.840.1.113762.1.4.1046.241): Deleted 1 RxNorm code (1372265) based on terminology update.

Terminology

Annual Update

Value set Schedule IV Benzodiazepines (2.16.840.1.113762.1.4.1125.1): Added 1 RxNorm code (317408) based on terminology update. Deleted 1 RxNorm code (763029) based on terminology update.

Terminology

Annual Update

Last Updated: May 06, 2025