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Appropriate Treatment for ST-Segment Elevation Myocardial Infarction (STEMI) Patients in the Emergency Department (ED)

Compare Versions of: "Appropriate Treatment for ST-Segment Elevation Myocardial Infarction (STEMI) Patients in the Emergency Department (ED)"

The Compare function compares two years of the measure specifications found in the header of the measure's HTML. It does not include a comparison of any information in the body of the HTML, e.g., population criteria, Clinical Quality Language, or value sets.

Strikethrough text highlighted in red indicates information changed from the previous version. Text highlighted in green indicates information updated in the new eCQM version.

Compare 2026 version to

Table Options
Measure Information 2026 Reporting Period
Title Appropriate Treatment for ST-Segment Elevation Myocardial Infarction (STEMI) Patients in the Emergency Department (ED)
CMS eCQM ID CMS996v6
CBE ID* 3613e
Measure Steward Centers for Medicare & Medicaid Services (CMS)
Description

Percentage of emergency department (ED) encounters for patients 18 years and older with a diagnosis of ST-segment elevation myocardial infarction (STEMI) that received appropriate treatment, defined as fibrinolytic therapy within 30 minutes of ED arrival, percutaneous coronary...

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Measure Scoring Proportion measure
Measure Type Process
Stratification

None

Risk Adjustment

None

Rationale

Studies have shown that delays in the treatment of acute myocardial infarction (AMI) leads to increased risk of in-hospital mortality and morbidity, with nearly two lives per 1,000 patients lost per hour of delay in treatment (Solhpour & Yusuf, 2013; Fibrinolytic Therapy Trialists’...

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Clinical Recommendation Statement

Primary PCI in STEMI:

The 2013 ACCF/AHA clinical practice guideline for the management of STEMI recommends that:

- "Primary PCI should be performed in patients with STEMI and ischemic symptoms of less than 12 hours’ duration."

- "Primary PCI should be performed in patients with STEMI and...

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Improvement Notation

Increased score indicates improvement

Definition

None

Guidance

In order to support the best outcomes for patients and align with other guidelines, PCI device deployment time should be used for calculating the “PCI is performed within 90 minutes of ED arrival” numerator criteria and not the start time of the procedure.

This eCQM is an episode-based...

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Initial Population

All emergency department encounters for patients 18 years and older at the start of the encounter with a diagnosis of ST-segment elevation myocardial infarction (STEMI) during an Emergency Department encounter that ends during the measurement period

Denominator

Equals Initial Population

Denominator Exclusions

Patients with the following conditions are excluded from measure denominator:

At some point during ED encounter:

- Allergic reaction to alteplase, streptokinase, anistreplase, tenecteplase, or reteplase

Starts before the start of ED encounter and does not end before ED encounter:

- Bleeding...

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Numerator

Emergency department encounters with a diagnosis of STEMI:

- where time from ED arrival to fibrinolysis is 30 minutes or fewer;

OR

- where PCI is performed within 90 minutes of arrival;

OR

- where the patient is discharged to an acute care facility within 45 minutes of ED arrival

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Numerator Exclusions

None

Denominator Exceptions

Emergency department encounters where the patient received fibrinolytic therapy at another facility within 24 hours.

Emergency department encounters with a documented reason for not administering fibrinolytic therapy within 30 minutes of ED arrival. 

Emergency department encounters with a...

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Next Version No Version Available
Previous Version

Header

TRN

Measure Section

Source of Change

Updated 'eCQM Identifier (Measure Authoring Tool)' field to 'CMS ID' based on tooling update.

CMS ID

Standards/Technical Update

Updated the eCQM version number.

eCQM Version Number

Annual Update

Updated measurement period to reflect exact dates of reporting.

Measurement Period

Standards/Technical Update

Updated measure developer from Yale New Haven Health Service Corporation/Center for Outcomes Research and Evaluation to Acumen, LLC.

Measure Developer

Annual Update

Updated Description to reflect inclusion criterion for when a patient is discharged to an acute care facility, aligning with measure intent.

Description

Annual Update

Updated copyright.

Copyright

Annual Update

Updated disclaimer.

Disclaimer

Annual Update

Removed the prefix 'proposed' when referring to the measure, as CMS has finalized the measure for reporting.

Rationale

Annual Update

Updated Improvement Notation field to read 'Increased score indicates improvement' based on tooling update to promote alignment across measures.

Improvement Notation

Standards/Technical Update

Added guidance on the use of device deployment time when calculating percutaneous coronary intervention performance in Numerator to align with measure intent.

Guidance

Measure Lead

Clarified that ischemic stroke, significant facial and/or closed head trauma, and peptic ulcer must occur 'within' 90 days before start of or at start of emergency department encounter to be excluded from the measure Denominator to better align with measure intent.

Denominator Exclusions

Measure Lead

Added diagnoses of angina pectoris with documented spasm, aneurysm of heart, ventricular aneurysm due to and following acute myocardial infarction, and Takotsubo cardiomyopathy or syndrome that occur 24 hours or less before start of emergency department encounter or during the emergency department encounter to Denominator Exclusion criteria to align with measure intent.

Denominator Exclusions

Measure Lead

Added a Denominator Exclusion for patients with documentation of hospice services in the six months within the start of the emergency department encounter or active hospice status at the start of the emergency department encounter to allow for consideration of patient/family decision-making in treatment.

Denominator Exclusions

Annual Update

Added a Denominator Exclusion for patients with a discharge disposition of 'Left Against Medical Advice' to better align with measure intent.

Denominator Exclusions

Measure Lead

Included 'or removal' in the Denominator Exclusion narrative definition for mechanical circulatory assist device placement to better align with measure intent.

Denominator Exclusions

Measure Lead

Rephrased the anticoagulant Denominator Exclusion in the header from 'At the start of ED encounter, or most recent dose within 90 days or less of ED encounter' to remove the phrase 'or most recent dose' to better align with measure intent.

Denominator Exclusions

Measure Lead

Updated the third component of the Numerator description to reflect inclusion criterion for when a patient is discharged to an acute care facility, aligning with measure intent.

Numerator

Measure Lead

Updated Numerator Exclusions field to read 'None' instead of 'Not Applicable' when no exclusions present to promote alignment across header fields.

Numerator Exclusions

Standards/Technical Update

Added two Denominator Exceptions to the measure for encounters with a documented reason for not administering fibrinolytic therapy within 30 minutes of emergency department arrival and a documented reason for not performing a percutaneous coronary intervention within 90 minutes of emergency department arrival to align with measure intent.

Denominator Exceptions

Measure Lead

Updated references and measure header to reflect current evidence and new or updated literature.

Multiple Sections

Measure Lead

Logic

TRN

Measure Section

Source of Change

Moved the Denominator age restriction of 18 years or older from the Initial Population definition to the 'ED Encounter During MP' definition to improve data processing times.

Initial Population

Annual Update

Added a Denominator Exclusion for patients with documentation of hospice services in the six months within the start of the emergency department encounter or active hospice status at the start of the emergency department encounter to align with the measure's clinical intent, reflected by the 'ED Encounter with Hospice Services' definition.

Denominator Exclusions

Annual Update

Added 'Device Placement or Removal' to the Denominator Exclusion definition for intubation or mechanical circulatory assist to better align with measure intent.

Denominator Exclusions

Measure Lead

Added new definitions, 'Active Use of Anticoagulants' and 'Active Long Term Use of Anticoagulants', for the Denominator Exclusion for active oral anticoagulant therapy to identify both active oral anticoagulant medication at the start of the emergency department encounter as well as active long-term use of anticoagulants to align with measure intent.

Denominator Exclusions

Measure Lead

Added a Denominator Exclusion for patients with a discharge disposition of 'Left Against Medical Advice,' reflected by the 'ED Encounter With Discharge Disposition As Left Against Medical Advice' definition, to better align with measure intent.

Denominator Exclusions

Measure Lead

Updated the definition name of the third component of the Numerator definition to 'ED Departure with Discharge To Acute Care Facility Within 45 Minutes of Arrival' to reflect inclusion criteria for when a patient is discharged to an acute care facility, aligning with measure intent.

Numerator

Annual Update

Added logic for two new Denominator Exceptions, reflected by the 'ED Encounter With A Documented Reason For Not Administering Fibrinolytic Therapy Within 30 Minutes Of ED Arrival' and 'ED Encounter With A Documented Reason For No PCI Performed Within 90 Minutes Of ED Arrival' definitions, to align with measure intent.

Denominator Exceptions

Measure Lead

Moved the Denominator age restriction of 18 years or older from the Initial Population definition to the 'ED Encounter During MP' definition to improve data processing times.

Definitions

Annual Update

Added a Denominator Exclusion for patients with a discharge disposition of 'Left Against Medical Advice,' reflected by the 'ED Encounter With Discharge Disposition As Left Against Medical Advice' definition, to better align with measure intent.

Definitions

Measure Lead

Consolidated three emergency department STEMI diagnosis definitions into a single definition called, 'ED Encounter With STEMI Diagnosis,' to streamline logic.

Definitions

Annual Update

Updated the version number of the Global Shared Library to v9.0.000 and the library name from 'MATGlobalCommonFunctionsQDM' to 'CQMCommonQDM'.

Definitions

Annual Update

Updated the measure's Clinical Quality Language (CQL) file to create a definition for the measure's Denominator Exceptions, resolving a known issue with the measure.

Definitions

Standards/Technical Update

Updated the CQL library name from 'CMS996-v5-1-000-QDM-5-6.cql' to 'CMS996AptTxforSTEMI-6.3.000.cql' based on recommendation by technical experts.

Definitions

Standards/Technical Update

Added a Denominator Exclusion for patients with documentation of hospice services in the six months within the start of the emergency department encounter or active hospice status at the start of the emergency department encounter to align with the measure's clinical intent, reflected by the 'ED Encounter with Hospice Services' definition.

Definitions

Annual Update

Updated the names of CQL definitions, functions, and/or aliases for clarification and to align with the CQL Style Guide.

Definitions

Standards/Technical Update

Added 'Device Placement or Removal' to the Denominator Exclusion definition for intubation or mechanical circulatory assist to better align with measure intent.

Definitions

Measure Lead

Updated the definition name of the third component of the Numerator definition to 'ED Departure with Discharge To Acute Care Facility Within 45 Minutes of Arrival' to reflect inclusion criteria for when a patient is discharged to an acute care facility, aligning with measure intent.

Definitions

Annual Update

Added new definitions, 'Active Use of Anticoagulants' and 'Active Long Term Use of Anticoagulants', for the Denominator Exclusion for active oral anticoagulant therapy to identify both active oral anticoagulant medication at the start of the emergency department encounter as well as active long term use of anticoagulants to align with measure intent.

Definitions

Measure Lead

Added diagnoses of angina pectoris with documented spasm, aneurysm of heart, ventricular aneurysm due to and following acute myocardial infarction, and Takotsubo cardiomyopathy or syndrome that occur 24 hours or less before start of emergency department encounter or during the emergency department encounter to Denominator Exclusion criteria to align with measure intent.

Definitions

Measure Lead

Added logic for two new Denominator Exceptions, reflected by the 'ED Encounter With A Documented Reason For Not Administering Fibrinolytic Therapy Within 30 Minutes Of ED Arrival' and 'ED Encounter With A Documented Reason For No PCI Performed Within 90 Minutes Of ED Arrival' definitions, to align with measure intent.

Definitions

Measure Lead

Updated the version number of the Global Shared Library to v9.0.000 and the library name from 'MATGlobalCommonFunctionsQDM' to 'CQMCommonQDM'.

Functions

Annual Update

Value Set

The VSAC is the source of truth for the value set content, please visit the VSAC for downloads of current value sets.

TRN

Measure Section

Source of Change

Replaced value set used for Sex Supplemental Data Element (SDE) ONC Administrative Sex (2.16.840.1.113762.1.4.1) with value set Federal Administrative Sex (2.16.840.1.113762.1.4.1021.121) based on updated standards.

Terminology

Standards/Technical Update

Added direct reference codes 4 ICD-10-CM codes (I25.3, I20.1, Z79.01, I51.81), 1 LOINC code (45755-6), and 5 SNOMED CT codes (428371000124100, 428361000124107, 441541008, 723858002, 373066001) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set (2.16.840.1.113883.3.3157.4036): Renamed to Active Bleeding or Bleeding Diathesis, Excluding Menses based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Active Bleeding or Bleeding Diathesis, Excluding Menses (2.16.840.1.113883.3.3157.4036): Added 3 ICD-10-CM codes (D65, D63.0, K92.0) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Allergy to thrombolytics (2.16.840.1.113762.1.4.1170.5): Added 2 SNOMED CT codes (1300135006, 1300136007) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Aortic Dissection or Ruptured Aortic Aneurysm (2.16.840.1.113883.3.3157.4028): Added 1 ICD-10-CM code (I71.010) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set (2.16.840.1.113883.3.3157.4048): Renamed to Cardiopulmonary Emergency based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Cardiopulmonary Emergency (2.16.840.1.113883.3.3157.4048): Added 3 ICD-10-CM codes (J96.00, J96.01, J96.02) based on review by technical experts, SMEs, and/or public feedback. Deleted 2 ICD-10-CM codes (I47.20, I47.29) based on review by technical experts, SMEs, and/or public feedback. Deleted 21 SNOMED CT codes based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Cerebral Vascular Lesion (2.16.840.1.113883.3.3157.4025): Added 1 ICD-10-CM code (C83.390) based on review by technical experts, SMEs, and/or public feedback. Added 1 SNOMED CT code (307649006) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Closed Head and Facial Trauma (2.16.840.1.113883.3.3157.4026): Added 3 SNOMED CT codes (127295002, 127304009, 127306006) based on terminology update. Added 1 SNOMED CT code (127298000) based on review by technical experts, SMEs, and/or public feedback. Deleted 12 SNOMED CT codes based on terminology update.

Terminology

Measure Lead

Value set Dementia and Related Intracranial Pathologies (2.16.840.1.113883.3.3157.4043): Added 9 SNOMED CT codes (142001000119106, 230288001, 429998004, 1259485008, 1259501004, 1259586006, 1339031006, 788898005, 833326008) based on review by technical experts, SMEs, and/or public feedback. Deleted 3 ICD-10-CM codes (F01.51, F02.81, F03.91) based on applicability of value set and/or OID.

Terminology

Measure Lead

Added value set Drug Intervention Not Indicated/Contraindicated (2.16.840.1.113762.1.4.1282.1) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Added value set Encounter Inpatient (2.16.840.1.113883.3.666.5.307) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Value set Endotracheal Intubation (2.16.840.1.113762.1.4.1045.69): Added 3 CPT codes (31500, 94002, 94003) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Added value set Hospice Care Ambulatory (2.16.840.1.113883.3.526.3.1584) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Added value set Hospice Diagnosis (2.16.840.1.113883.3.464.1003.1165) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Added value set Hospice Encounter (2.16.840.1.113883.3.464.1003.1003) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Value set Intracranial or Intraspinal surgery (2.16.840.1.113762.1.4.1170.2): Added 9 SNOMED CT codes (273990004, 1287541008, 1296603004, 1296604005, 1296605006, 1296606007, 1296607003, 1296608008, 1296626006) based on terminology update. Deleted 8 SNOMED CT codes (19994000, 21205002, 243570009, 27968003, 34719005, 51991009, 79272003, 80460006) based on terminology update.

Terminology

Annual Update

Added value set Left Against Medical Advice (2.16.840.1.113883.3.117.1.7.1.308) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Value set Major Surgical Procedure (2.16.840.1.113883.3.3157.4056): Added 18 ICD-10-PCS codes based on terminology update. Deleted 32 ICD-10-PCS codes based on review by technical experts, SMEs, and/or public feedback. Added 373 SNOMED CT codes based on terminology update. Deleted 265 SNOMED CT codes based on terminology update.

Terminology

Measure Lead

Value set (2.16.840.1.113883.3.3157.4052): Renamed to Mechanical Circulatory Assist Device based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Mechanical Circulatory Assist Device (2.16.840.1.113883.3.3157.4052): Added 2 SNOMED CT codes (427198005, 426410001) based on review by technical experts, SMEs, and/or public feedback. Added 39 ICD-10-PCS codes based on review by technical experts, SMEs, and/or public feedback. Added 10 CPT codes (33967, 33968, 33971, 33973, 33974, 33977, 33978, 33980, 33992, 33997) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Added value set Patient Refusal (2.16.840.1.113883.3.117.1.7.1.93) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Value set Percutaneous Coronary Intervention (2.16.840.1.113883.3.3157.2000.5): Added 7 SNOMED CT codes (1222571004, 1222673007, 1222674001, 24088005, 410023005, 709981002, 415069007) based on review by technical experts, SMEs, and/or public feedback. Added 2 CPT codes (0913T, 0914T) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Value set Pregnant State (2.16.840.1.113883.3.3157.4055): Added 1 SNOMED CT code (77386006) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Added value set Procedure Not Indicated/Contraindicated (2.16.840.1.113762.1.4.1282.2) based on change in measure requirements/measure specification.

Terminology

Measure Lead

Value set Thrombolytics Adverse Event (2.16.840.1.113762.1.4.1170.6): Added 2 SNOMED CT codes (1300134005, 1300137003) based on review by technical experts, SMEs, and/or public feedback.

Terminology

Measure Lead

Last Updated: May 06, 2025