eCQM Title | Appropriate Use of DXA Scans in Women Under 65 Years Who Do Not Meet the Risk Factor Profile for Osteoporotic Fracture |
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eCQM Identifier (Measure Authoring Tool) | 249 | eCQM Version Number | 3.2.000 |
NQF Number | 3475e | GUID | a3ce125d-c238-42ce-862e-dba0055dfc66 |
Measurement Period | January 1, 20XX through December 31, 20XX | ||
Measure Steward | Centers for Medicare & Medicaid Services (CMS) | ||
Measure Developer | National Committee for Quality Assurance | ||
Endorsed By | National Quality Forum | ||
Description |
Percentage of female patients 50 to 64 years of age without select risk factors for osteoporotic fracture who received an order for a dual-energy x-ray absorptiometry (DXA) scan during the measurement period |
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Copyright |
This Physician Performance Measure (Measure) and related data specifications are owned and stewarded by the Centers for Medicare & Medicaid Services (CMS). This measure was developed under CMS Contract No. HHSM-500-2013-13011I, Task Order HHSM-500-TO0001. Mathematica and the National Committee for Quality Assurance (NCQA) supported development of this electronic measure. NCQA is not responsible for any use of the Measure. NCQA makes no representations, warranties, or endorsement about the quality of any organization or physician that uses or reports performance measures and NCQA has no liability to anyone who relies on such measures or specifications. Limited proprietary coding is contained in the Measure specifications for user convenience. Users of proprietary code sets should obtain all necessary licenses from the owners of the code sets. NCQA disclaims all liability for use or accuracy of any third party codes contained in the specifications. CPT(R) contained in the Measure specifications is copyright 2004-2019 American Medical Association. LOINC(R) copyright 2004-2019 Regenstrief Institute, Inc. This material contains SNOMED Clinical Terms(R) (SNOMED CT[R]) copyright 2004-2019 International Health Terminology Standards Development Organisation. ICD-10 copyright 2019 World Health Organization. All Rights Reserved. |
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Disclaimer |
The performance Measure is not a clinical guideline and does not establish a standard of medical care, and has not been tested for all potential applications. THE MEASURE AND SPECIFICATIONS ARE PROVIDED "AS IS" WITHOUT WARRANTY OF ANY KIND. Due to technical limitations, registered trademarks are indicated by (R) or [R] and unregistered trademarks are indicated by (TM) or [TM]. |
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Measure Scoring | Proportion | ||
Measure Type | Process | ||
Stratification |
None |
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Risk Adjustment |
None |
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Rate Aggregation |
None |
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Rationale |
This measure is expected to increase recording of patient risk for fracture data and decrease the amount of inappropriate DXA scans. Current osteoporosis guidelines recommend using bone measurement testing to assess osteoporosis risk in women 65 years and older. In postmenopausal women younger than age 65, guidelines recommend using a formal clinical risk assessment tool to establish a patient's risk for osteoporosis, in order to determine whether to screen a patient for osteoporosis using bone measurement testing. Clinical information, such as age, body mass index (BMI), parental hip fracture history, and smoking and alcohol use, can be used to determine a woman's fracture risk (U.S. Preventive Services Task Force [USPSTF], 2018). Additionally, there are potentially avoidable harms associated with screening for osteoporosis in general, including exposure to radiation, false positive exams, and resulting side effects from unnecessary osteoporosis medications, which add costs to an already burdened health care system (Lim, Hoeksema, & Sherin, 2009). |
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Clinical Recommendation Statement |
USPSTF: "The USPSTF recommends screening for osteoporosis with bone measurement testing to prevent osteoporotic fractures in women 65 years and older." This is a B recommendation. "The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for osteoporosis to prevent osteoporotic fractures in men." This is an I statement. "Several tools are available to assess osteoporosis risk: the Simple Calculated Osteoporosis Risk Estimate (SCORE; Merck), Osteoporosis Risk Assessment Instrument (ORAI), Osteoporosis Index of Risk (OSIRIS), and the Osteoporosis Self-Assessment Tool (OST). These tools seem to perform similarly and are moderately accurate at predicting osteoporosis. The FRAX tool (University of Sheffield), which assesses a person's 10-year risk of fracture, is also a commonly used tool." "The USPSTF recommends screening for osteoporosis with bone measurement testing to prevent osteoporotic fractures in postmenopausal women younger than 65 years who are at increased risk of osteoporosis, as determined by a formal clinical risk assessment tool." This is a B recommendation. "For postmenopausal women younger than 65 years who have at least 1 risk factor, a reasonable approach to determine who should be screened with bone measurement testing is to use a clinical risk assessment tool." "Because the benefits of treatment are greater in persons at higher risk of fracture, one approach is to perform bone measurement testing in postmenopausal women younger than 65 years who have a 10-year FRAX risk of major osteoporotic fracture (MOF) (without DXA) greater than that of a 65-year-old white woman without major risk factors. For example, in the United States, a 65-year-old white woman of mean height and weight without major risk factors has a 10-year FRAX risk of MOF of 8.4%." The National Institute for Health and Clinical Excellence’s Osteoporosis Guidelines: "Consider assessment of fracture risk: a. in all women aged 65 years and over and all men aged 75 years and over b. in women aged under 65 years and men aged under 75 years in the presence of risk factors, for example: *previous fragility fracture *current use or frequent/ recent use of oral or systemic glucocorticoids *history of falls *family history of hip fracture *other causes of secondary osteoporosis *low body mass index (BMI) (less than 18.5 kg/m2) *smoking *alcohol intake of more than 14 units per week for women and more than 21 units per week for men." "Do not routinely assess fracture risk in people aged under 50 years unless they have major risk factors (for example, current or frequent/recent use of oral or systemic glucocorticoids, untreated premature menopause or previous fragility fracture), because they are unlikely to be at high risk." "Estimate absolute risk when assessing risk of fracture (for example, the predicted risk of major osteoporotic or hip fracture over 10 years, expressed as a percentage." "Use either FRAX (without a bone mineral density [BMD] value if a dual energy X-ray absorptiometry [DXA] scan has not previously been undertaken) or QFracture, within their allowed age ranges, to estimate 10-year predicted absolute fracture risk when assessing risk of fracture." "Do not routinely measure BMD to assess fracture risk without prior assessment using FRAX (without a BMD value) or QFracture." "Take into account that risk assessment tools may underestimate fracture risk in certain circumstances, for example if a person: *has a history of multiple fractures *has had previous vertebral fracture(s) *has a high alcohol intake *is taking high-dose oral or high-dose systemic glucocorticoids (more than 7.5 mg prednisolone or equivalent per day for 3 months or longer) *has other causes of secondary osteoporosis." |
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Improvement Notation |
Lower score indicates better quality |
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Reference |
Lim, L. S., Hoeksema, L. J., & Sherin, K. (2009). Screening for osteoporosis in the adult U.S. population: ACPM position statement on preventive practice. American Journal of Preventive Medicine, 36(4), 366-375. |
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Reference |
National Institute for Health and Clinical Excellence. (2017). Osteoporosis: Fragility fracture risk. Retrieved from https://www.nice.org.uk/guidance/cg146/chapter/1-Guidance |
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Reference |
U.S. Preventive Services Task Force, Curry S. J., Krist, A. H., et al. (2018). Screening for osteoporosis to prevent fractures: U.S. Preventive Services Task Force recommendation statement. JAMA, 319(24), 2521-2531. |
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Definition |
The measure allows for clinicians to use the Fracture Risk Assessment Tool (FRAX[R]) to calculate 10-year absolute fracture risk. The FRAX was developed by the World Health Organization in 2008 to evaluate a patient's 10-year probability of hip fracture and major osteoporotic fracture (clinical spine, forearm, hip, or shoulder fracture). It is applicable to people aged 40-90 years. |
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Guidance |
There are two ways that a patient can be excluded from the measure: 1. The patient has a specific number of "combination" risk factors (the number of risk factors varies by age). 2. The patient has one or more of the "independent" risk factors, including a 10-year probability of major osteoporotic fracture of 8.4 percent or higher as determined by the FRAX. This eCQM is a patient-based measure. This version of the eCQM uses QDM version 5.5. Please refer to the eCQI resource center (https://ecqi.healthit.gov/qdm) for more information on the QDM. |
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Transmission Format |
TBD |
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Initial Population |
Female patients ages 50 to 64 years with an encounter during the measurement period |
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Denominator |
Equals Initial Population |
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Denominator Exclusions |
Exclude patients with a combination of risk factors (as determined by age) or one of the independent risk factors Ages: 50-54 (>=4 combination risk factors) or 1 independent risk factor Ages: 55-59 (>=3 combination risk factors) or 1 independent risk factor Ages: 60-64 (>=2 combination risk factors) or 1 independent risk factor COMBINATION RISK FACTORS [The following risk factors are all combination risk factors; they are grouped by when they occur in relation to the measurement period]: The following risk factors may occur any time in the patient's history but must be active during the measurement period: White (race) BMI <= 20 kg/m2 (must be the first BMI of the measurement period) Smoker (current during the measurement period) Alcohol consumption (> two units per day (one unit is 12 oz. of beer, 4 oz. of wine, or 1 oz. of liquor)) The following risk factor may occur any time in the patient's history and must not start during the measurement period: Osteopenia The following risk factors may occur at any time in the patient's history or during the measurement period: Rheumatoid arthritis Hyperthyroidism Malabsorption Syndromes: celiac disease, inflammatory bowel disease, ulcerative colitis, Crohn's disease, cystic fibrosis, malabsorption Chronic liver disease Chronic malnutrition The following risk factors may occur any time in the patient's history and do not need to be active at the start of the measurement period: Documentation of history of hip fracture in parent Osteoporotic fracture Glucocorticoids (>= 5 mg/per day) [cumulative medication duration >= 90 days] INDEPENDENT RISK FACTORS (The following risk factors are all independent risk factors; they are grouped by when they occur in relation to the measurement period): The following risk factors may occur at any time in the patient's history and must not start during the measurement period: Osteoporosis The following risk factors may occur at any time in the patient's history prior to the start of the measurement period, but do not need to be active during the measurement period: Gastric bypass FRAX[R] ten-year probability of all major osteoporosis related fracture >= 8.4 percent Aromatase inhibitors The following risk factors may occur at any time in the patient's history or during the measurement period: Type I Diabetes End stage renal disease Osteogenesis imperfecta Ankylosing spondylitis Psoriatic arthritis Ehlers-Danlos syndrome Cushing's syndrome Hyperparathyroidism Marfan syndrome Lupus |
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Numerator |
Female patients who received an order for at least one DXA scan in the measurement period |
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Numerator Exclusions |
Not Applicable |
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Denominator Exceptions |
None |
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Supplemental Data Elements |
For every patient evaluated by this measure also identify payer, race, ethnicity and sex |
exists ["Patient Characteristic Birthdate": "Birth date"] BirthDate where Global."CalendarAgeInYearsAt" ( BirthDate.birthDatetime, start of "Measurement Period" ) in Interval[50, 64 ) and exists ( ["Patient Characteristic Sex": "Female"] ) and exists "Qualifying Encounter"
"Initial Population"
"Has Age Dependent Combination Risk Factors" or "Has Osteoporosis Before Measurement Period" or "Has Independent Risk Factors Applicable Any Time" or "Has Independent Risk Factors Before Measurement Period"
exists ["Diagnostic Study, Order": "DXA (Dual energy Xray Absorptiometry) Scan"] DXA where DXA.authorDatetime during "Measurement Period"
None
None
None
"Combination Risk Factors Applicable Any Time" union "Osteoporotic Fracture From Patient History" union "Parent History of Hip Fracture Assessment" union "Osteopenia Before Measurement Period" union "First Tobacco Use Screening Indicating Current Smoker" union "First Average Number of Drinks Assessments Indicating More Than Two Per Day" union "First BMI in Measurement Period Less Than or Equal to 20 kg m2" union ["Patient Characteristic Race": "White"]
( ["Diagnosis": "Rheumatoid Arthritis"] union ["Diagnosis": "Hyperthyroidism"] union ["Diagnosis": "Malabsorption Syndromes"] union ["Diagnosis": "Chronic Liver Disease"] union ["Diagnosis": "Chronic Malnutrition"] ) CombinationRiskDiagnosis where CombinationRiskDiagnosis.prevalencePeriod starts before end "Measurement Period"
"Initial Population"
"Has Age Dependent Combination Risk Factors" or "Has Osteoporosis Before Measurement Period" or "Has Independent Risk Factors Applicable Any Time" or "Has Independent Risk Factors Before Measurement Period"
{ First(["Assessment, Performed": "Average Number of Drinks per Drinking Day"] AverageDrinks where AverageDrinks.relevantDatetime during "Measurement Period" and AverageDrinks.result > 2 '{drinks}/d' sort by relevantDatetime )}
{ First(["Physical Exam, Performed": "BMI Ratio"] BMI where BMI.relevantDatetime during "Measurement Period" and BMI.result is not null sort by relevantDatetime )}
"First BMI in Measurement Period" FirstBMI where FirstBMI.result <= 20 'kg/m2'
{ First(["Assessment, Performed": "Tobacco Use Screening"] TobaccoScreen where TobaccoScreen.result in "Current Tobacco Smoker" and TobaccoScreen.relevantDatetime during "Measurement Period" sort by relevantDatetime )}
["Medication, Active": "Glucocorticoids (oral only)"] Glucocorticoid where Glucocorticoid.relevantPeriod starts before end of "Measurement Period"
"Glucocorticoid Medication Active" MedicationGlucocorticoid let dosesPerDay: "DosesPerDay"(MedicationGlucocorticoid.frequency), dailyDosage: "GetMedicationDailyDose"(MedicationGlucocorticoid.dosage, dosesPerDay), medPeriod: MedicationGlucocorticoid.relevantPeriod intersect Interval[start of MedicationGlucocorticoid.relevantPeriod, end of "Measurement Period"] return Tuple { code: MedicationGlucocorticoid.code, daysInPeriod: expand { medPeriod } per day, dailyDosage: dailyDosage }
( distinct ( flatten ( "Glucocorticoids Daily Dosage Per Medication" GlucocorticoidsDailyDosage return all GlucocorticoidsDailyDosage.daysInPeriod ) ) ) Day return { medicationDay: Day, totalDailyDosage: Sum("Glucocorticoids Daily Dosage Per Medication" GlucocorticoidsDailyDosagePerDay where Day in GlucocorticoidsDailyDosagePerDay.daysInPeriod return all GlucocorticoidsDailyDosagePerDay.dailyDosage ) }
Count("Glucocorticoids Dosage Per Day" GlucocorticoidsDosage where GlucocorticoidsDosage.totalDailyDosage >= 5 'mg/d' )>= 90
singleton from ( ["Patient Characteristic Birthdate": "Birth date"] BirthDate let Age: Global."CalendarAgeInYearsAt" ( BirthDate.birthDatetime, start of "Measurement Period" ), NumberOfRiskFactors: Count("Age Dependent Combination Risk Factors")+ ( if "Glucocorticoids Greater Than 5 MG per Day for 90 or More Days" then 1 else 0 ) return ( ( Age between 50 and 54 and NumberOfRiskFactors >= 4 ) or ( Age between 55 and 59 and NumberOfRiskFactors >= 3 ) or ( Age between 60 and 63 and NumberOfRiskFactors >= 2 ) ) )
exists ( ["Diagnosis": "Type 1 Diabetes"] union ["Diagnosis": "End Stage Renal Disease"] union ["Diagnosis": "Osteogenesis Imperfecta"] union ["Diagnosis": "Ankylosing Spondylitis"] union ["Diagnosis": "Psoriatic Arthritis"] union ["Diagnosis": "Ehlers Danlos Syndrome"] union ["Diagnosis": "Cushings Syndrome"] union ["Diagnosis": "Marfan's Syndrome"] union ["Diagnosis": "Hyperparathyroidism"] union ["Diagnosis": "Lupus"] ) IndependentRiskDiagnosis where IndependentRiskDiagnosis.prevalencePeriod starts before end "Measurement Period"
exists ( ( ( ["Procedure, Performed": "Gastric Bypass Surgery"] union ["Medication, Active": "Aromatase Inhibitors"] union ["Medication, Order": "Aromatase Inhibitors"] ) GastricBypassOrAromataseInhibitor where GastricBypassOrAromataseInhibitor.relevantPeriod starts before start "Measurement Period" ) union "Osteoporosis Fracture Probability Assessment" )
exists ["Diagnosis": "Osteoporosis"] OsteoporosisDiagnosis where OsteoporosisDiagnosis.prevalencePeriod overlaps before "Measurement Period"
exists ["Patient Characteristic Birthdate": "Birth date"] BirthDate where Global."CalendarAgeInYearsAt" ( BirthDate.birthDatetime, start of "Measurement Period" ) in Interval[50, 64 ) and exists ( ["Patient Characteristic Sex": "Female"] ) and exists "Qualifying Encounter"
exists ["Diagnostic Study, Order": "DXA (Dual energy Xray Absorptiometry) Scan"] DXA where DXA.authorDatetime during "Measurement Period"
["Diagnosis": "Osteopenia"] OsteopeniaDiagnosis where OsteopeniaDiagnosis.prevalencePeriod starts before start "Measurement Period"
["Assessment, Performed": "Major osteoporotic fracture 10-year probability [Likelihood] Fracture Risk Assessment"] ProbabilityAssessment where ProbabilityAssessment.result >= 8.4 '%' and ProbabilityAssessment.relevantDatetime before start of "Measurement Period"
( ["Diagnosis": "Osteoporotic Fractures"] PathologicalFracture where PathologicalFracture.prevalencePeriod starts before start "Measurement Period" )
["Assessment, Performed": "History of hip fracture in parent"] ParentFractureHistory where ParentFractureHistory.relevantDatetime before start of "Measurement Period"
( ["Encounter, Performed": "Office Visit"] union ["Encounter, Performed": "Preventive Care Services - Established Office Visit, 18 and Up"] union ["Encounter, Performed": "Preventive Care Services - Other"] union ["Encounter, Performed": "Preventive Care Services-Initial Office Visit, 18 and Up"] union ["Encounter, Performed": "Outpatient Consultation"] ) ValidEncounter where ValidEncounter.relevantPeriod during "Measurement Period"
["Patient Characteristic Ethnicity": "Ethnicity"]
["Patient Characteristic Payer": "Payer"]
["Patient Characteristic Race": "Race"]
["Patient Characteristic Sex": "ONC Administrative Sex"]
case when frequency ~ "Once daily (qualifier value)" then 1.0 when frequency ~ "Twice a day (qualifier value)" then 2.0 when frequency ~ "Three times daily (qualifier value)" then 3.0 when frequency ~ "Four times daily (qualifier value)" then 4.0 when frequency ~ "Every twenty four hours (qualifier value)" then 1.0 when frequency ~ "Every twelve hours (qualifier value)" then 2.0 when frequency ~ "Every thirty six hours (qualifier value)" then 0.67 when frequency ~ "Every eight hours (qualifier value)" then 3.0 when frequency ~ "Every four hours (qualifier value)" then 6.0 when frequency ~ "Every six hours (qualifier value)" then 4.0 when frequency ~ "Every seventy two hours (qualifier value)" then 0.34 when frequency ~ "Every forty eight hours (qualifier value)" then 0.5 when frequency ~ "Every eight to twelve hours (qualifier value)" then 2.0 when frequency ~ "Every six to eight hours (qualifier value)" then 3.0 when frequency ~ "Every three to four hours (qualifier value)" then 6.0 when frequency ~ "Every three to six hours (qualifier value)" then 4.0 when frequency ~ "Every two to four hours (qualifier value)" then 6.0 when frequency ~ "One to four times a day (qualifier value)" then 4.0 when frequency ~ "One to three times a day (qualifier value)" then 3.0 when frequency ~ "One to two times a day (qualifier value)" then 2.0 when frequency ~ "Two to four times a day (qualifier value)" then 4.0 else null end
dosage * Quantity { value: dosesPerDay, unit: '/d' }
years between ToDate(BirthDateTime)and ToDate(AsOf)
DateTime(year from Value, month from Value, day from Value, 0, 0, 0, 0, timezoneoffset from Value)
["Patient Characteristic Ethnicity": "Ethnicity"]
["Patient Characteristic Payer": "Payer"]
["Patient Characteristic Race": "Race"]
["Patient Characteristic Sex": "ONC Administrative Sex"]
Measure Set |
None |
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